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Tripos Inc sybyl mol2 files
Sybyl Mol2 Files, supplied by Tripos Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sybyl+mol2+files/sybyl+mol2+files/pmc10385924-27-10-16
Average 90 stars, based on 1 article reviews
sybyl mol2 files - by Bioz Stars, 2026-09
90/100 stars

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Article Title: PyL3dMD: Python LAMMPS 3D molecular descriptors package.
Article Snippet: For calculating 3D descriptors, the available molecular file formats include Sybyl MOL2 files (.mol,. ml2, mol2) by Tripos, Inc., Sybyl Molfiles (.sm2) by ChemOffice, CambridgeSoft Corp., Multiple SD files (.sdf ) by Molecular Design Ltd., HyperChem files (.hin) by Hypercube, Inc., MacroModel files by Schrodinger [24].

Article Title: Construction and Test of Ligand Decoy Sets Using MDock: Community Structure–Activity Resource Benchmarks for Binding Mode Prediction
Article Snippet: MDock is an automated molecular docking program (http://zoulab.dalton.missouri.edu/software.htm) which integrates the fast ensemble docking algorithm for multiple protein structures22,23 and the efficient ITScore scoring function for protein ligand interactions.9,10 The program suite uses the commonly used Sybyl (Tripos, Inc.) mol2 files of the protein and the ligand as input, in which hydrogens and atomic charges are optional, and their effects will be ignored when they are present during docking/scoring calculations.

Article Title: Efficacy and selectivity in flexible database docking
Article Snippet: Flexible database docking with DOCK 4.0 has been evaluated for its ability to retrieve biologically active molecules from a database of approximately 1,000 compounds with known activities against thrombin and the progesterone receptor.. The retrieval of known actives and chemically similar but inactive molecules was monitored as a function of conformational and orientational sampling.. The largest enrichment of actives among the 10% highest ranking molecules is obtained when only five conformations are used to seed the next round of ligand reconstruction and limited sampling is applied to place the base fragment in the binding site.

Article Title: PyL3dMD: Python LAMMPS 3D molecular descriptors package
Article Snippet: For calculating 3D descriptors, the available molecular file formats include Sybyl MOL2 files (.mol,.ml2, mol2) by Tripos, Inc., Sybyl Molfiles (.sm2) by ChemOffice, CambridgeSoft Corp., Multiple SD files (.sdf) by Molecular Design Ltd., HyperChem files (.hin) by Hypercube, Inc., MacroModel files by Schrodinger [ ].



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